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Kuipper. Discussion, the 31yearold female patient in this study developed hypercalcaemia and persistent renal impairment following resolution of pregnancyrelated ARF. A presumptive diagnosis of druginduced granulomatous interstitial nephritis was made. Twitter: @GrantHBrennerMD, linkedIn: website:.
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Drug hypersensitivity is a major cause of AIN with penicillins, cephalosporins and nonsteroidal antiinflammatory drugs (nsaids) being the most commonly implicated drugs. Acute interstitial nephritis (AIN) is identified in up to 15 of patients who undergo a renal biopsy for investigation of ARF. First of all, they found that most participants were disappointed after the first date, as indicated by having less attraction after meeting than during online engagement.
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This revealed a diffuse mixed inflammatory infiltrate with several noncaseating granulomata localized around damaged tubules. Radiological investigations including a chest radiograph and a parathyroid gland uptake scan were normal. Serum angiotensinconverting enzyme was 119 IU/l (normal range 25113 IU/l). Aust Ned 1994 ; 24 : 578 Google Scholar 11 Fleury D, Storkebaum H, Mougenot B. Drug withdrawal is the recommended treatment for druginduced AIN but there is anecdotal evidence that concomitant steroid therapy may aid recovery of renal function. Omeprazole, musculoskeletal problems and interstitial nephritis.
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